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Selegiline is a revolutionary medication for me because during my long years of 'collaboration' with depression it was the only medication that managed to improve my condition without causing serious side effects like drowsiness or vomiting. I take it on a regular basis two times per year and with this drug I can feel myself to be an absolutely normal person. Quite a new sensation for me.)
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Having tried just about everything out there, I was using an MAOI for years, but didn't realize how foggy I was feeling until I started using the Emsam patches. I can think more clearly, which is huge, but I still have to really push to do most things. They are the best thing I've tried.

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The increase in blood pressure was only slightly greater for subjects gorging on tyramine with the 6 mg EMSAM patch than for those who ingested tyramine while taking the control drugs, 20 mg fluoxetine or 10 mg oral selegiline.

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EMSAM or placebo at a starting dose of 6 mg per 24 hours, with possible increases to 9 mg per 24 hours or 12 mg per 24 hours based on clinical response, showed significant improvement compared with placebo on the primary outcome measure, the 28-item HAM-D total score (Study 2 in Table 7).

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EMSAM is a skin patch (transdermal system) used to treat major depression.

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Do not use sertraline if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days.

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