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Ranexa stopped the angina and I felt much better but the side effects were awful. Severe confusion, memory loss, vomiting, increased urination (so much so I was up every hour or so at night).



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I have chronic angina and for me the ideal medication is Ranolazine. The diagnosis was a shock for me in spite of the fact that I didn't have any bothering symptoms, slight tightness in my chest from time to time, difficuly when breathing, but I thought that was due to recent cold. However the doctor explained me that there were problems with my heart and it didn't get enough oxygen with the blood. Therefore I had to take certain medications to support my arteries and their functions. With Ranolazine my symptoms are easy to control I can prevent another attack of chest pain and live as if there is no angina. But when it is cold outside or too humid I can not breathe normally and afterwards still get some pain in the chest. But I am alive and I have no critical condition and I am grateful to Ranolazine for these facts. What is also very important for me is that I can sleep well at night without waking up suffocating. Recommend it to other angina victims.

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Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for and dizziness.

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Given that it potently recruited muscle microvasculature, suggesting a vasodilatatory effect on the pre-capillary arterioles, we tested ranolazine's effect on isolated distal saphenous artery.

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Exercise provides a more physiological environment than pharmacological tests and provides additional physiological data, such as exercise time and workload, as well as information about changes in heart rate, blood pressure and ECG.

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Continuous efficacy end points were analyzed using a mixed-models repeated-measures approach, which accounts for correlations among observations within a subject, allows for baseline adjustment, and uses all available data collected at various time points, including data from participants not completing week 24.

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